The Lancet, Volume 365, Issue 9477, Pages 2091 - 2097, 18 June 2005

MERIT study investigators ‡

Summary

Background
Patients with cardiac arrests or who die in general wards have often received delayed or inadequate care. We investigated whether the medical emergency team (MET) system could reduce the incidence of cardiac arrests, unplanned admissions to intensive care units (ICU), and deaths.
Methods
We randomised 23 hospitals in Australia to continue functioning as usual (n=11) or to introduce a MET system (n=12). The primary outcome was the composite of cardiac arrest, unexpected death, or unplanned ICU admission during the 6-month study period after MET activation. Analysis was by intention to treat.
Findings
Introduction of the MET increased the overall calling incidence for an emergency team (3·1 vs 8·7 per 1000 admissions, p=0·0001). The MET was called to 30% of patients who fulfilled the calling criteria and who were subsequently admitted to the ICU. During the study, we recorded similar incidence of the composite primary outcome in the control and MET hospitals (5·86 vs 5·31 per 1000 admissions, p=0·640), as well as of the individual secondary outcomes (cardiac arrests, 1·64 vs 1·31, p=0·736; unplanned ICU admissions, 4·68 vs 4·19, p=0·599; and unexpected deaths, 1·18 vs 1·06, p=0·752). A reduction in the rate of cardiac arrests (p=0·003) and unexpected deaths (p=0·01) was seen from baseline to the study period for both groups combined.
Interpretation
The MET system greatly increases emergency team calling, but does not substantially affect the incidence of cardiac arrest, unplanned ICU admissions, or unexpected death.